Postdoctoral Scholar in Alzheimer’s Disease/Neurodegeneration

Position Overview

School / Campus / College: School of Medicine

Organization: Medicine, Medical Genetics

Title: Postdoctoral Scholar in Alzheimer’s Disease/Neurodegeneration

Position Details

Position Description

The Raskind lab in the UW Division of Medical Genetics is seeking postdoctoral researchers with an interest in the functional genetics of neurodegenerative diseases to join ongoing studies of 1) the role of (H+) vacuolar ATPase in Parkinson’s disorder and intellectual disability (PMID:23595882); 2) microglia-specific genetic risk factors in Alzheimer’s disease (PMID: 26076170); 3) pathogeneses of movement disorders, such as ataxia and dystonia. Dr. Raskind and her team have had a major role in the identification and functional characterization of 15 disease genes. We use diverse functional assays based on induced pluripotent stem cells (iPSC) from patients, mouse models and OMICs analyses of brain tissues.

The UW is an outstanding environment from which future careers in academics and/or industry are strongly developed. The positions are supported by T32 training program and emphasize interdisciplinary basic science research training for a minimal period of two years for qualified individuals who are committed to pursuing a career in academic setting. Because the positions will be funded by an NIH institutional training grant, only US citizens or permanent residents are eligible. This position is a 12 months appointment position. 

Postdoctoral scholars are represented by UAW 4121 and are subject to the collective bargaining agreement, unless agreed exclusion criteria apply. For more information, please visit the University of Washington Labor Relations website:

https://hr.uw.edu/labor/academic-and-student-unions/uaw-postdocs/uaw-postdoc-contract

Qualifications

• Recent PhD in Neuroscience, Molecular and Cell Biology, Genome Sciences, Immunology or equivalent.
• Expertise in mammalian tissue culture, gene delivery (e.g., nucleofection, lentiviral vectors), RNA interference, in vivo reporter assays, flow cytometry and cell imaging.
• Practical knowledge of molecular cloning, Western blotting/ELISA, qRT-PCR, familiarity with next-gen sequencing
• Hands-on experience in neuropathology, including tissue fixation, IHC, fluorescence and confocal microscopy and image data processing and analysis, experience with mouse models or organotypic slice cultures.

Desired: expertise in stem cell biology (iPSC generation and differentiation), microglial and neuronal cultures, gene editing (CRISPR/CAS9), familiarity with bioinformatic tools for analysis of RNA-Seq or other OMICs data.

Instructions

Application should include a cover letter, CV and contact information for three references.

Equal Employment Opportunity Statement

University of Washington is an affirmative action and equal opportunity employer. All
qualified applicants will receive consideration for employment without regard to race, color, creed,
religion, national origin, sex, sexual orientation, marital status, pregnancy, genetic information,
gender identity or expression, age, disability, or protected veteran status.